The Essential Building Block for Conformationally Constrained Peptide Synthesis is Fmoc-Oic-OH

 

The need for artificial amino acids that make therapeutic peptides rigid and biostable is higher than ever in the field of contemporary peptide synthesis. Fmoc-Oic-OH( CAS: 130309-37-4) stands out as a high-value derivative out of these specialty building blocks.

This compound, which is known as( S) -N-9-Fluorenylmethyloxycarbonyl) -octahydroindole-2-carboxylic acid, is a conformationally restricted amino acid necessary for the development of next-generation peptide therapeutics.


Fmoc-Oic-OH Chemical Characteristics and Properties

A fused bicyclic octahydroindole band construction substantially limits the protein backbone's freedom, which is characteristic of Fmoc-Oic-OH. CAS No. 130309-37-4 C24H25NO4 Molecular Formula Chemical Weight: 391.46– 3911. 5 g/mol -1-9H-fluoren-9-ylmethoxycarbonyl) -2, 3, 3, 4, 5, 6, 7, 7a-octahydroindole-2-carboxylic acid( 2S, 3aS, 7aS) Beauty is typically available for applications of research quality between 98% and 91%. 


Appearance: Good powder that is light to off-white. Note on Isomers: While the industry standard for most peptidomimetics is the L-isomer( 130309-37-4), there are also D-isomers( CAS: 134526-62-8) for specific structure-activity relationship( SAR) studies.



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